💊 Prolavir-LR (Lopinavir & Ritonavir Tablets)

📌 What Is Prolavir-LR?

• Prolavir-LR is an antiretroviral medicine used in the treatment of HIV-1 infection.

• It is a fixed-dose combination of:

  • Lopinavir – a protease inhibitor.

  • Ritonavir – a protease inhibitor that mainly acts as a pharmacokinetic booster (increases lopinavir levels).

• This combination helps to lower viral load, improve CD4 cell count, and slow down disease progression.

💊 Pharmacological Action

🔹 Lopinavir

• Class: Protease Inhibitor (PI).

• Action: Blocks the HIV protease enzyme, which is essential for the cleavage of viral polyproteins into mature proteins.

• Effect: Produces immature, non-infectious viral particles, thereby stopping HIV replication.

🔹 Ritonavir

• Class: Protease Inhibitor (booster).

• Action: Strongly inhibits CYP3A4 enzyme in the liver → reduces lopinavir metabolism → increases lopinavir concentration in the blood.

• Effect: Enhances the efficacy and duration of lopinavir, making the combination more potent.

🩺 How To Take Prolavir-LR?

• Usually prescribed twice daily with food.

• Must be taken regularly at the same time each day.

• Always used as part of combination antiretroviral therapy (ART) under medical supervision.

🌟 Benefits Of Prolavir-LR

• ✔️ Potent protease inhibitor combo for HIV treatment.

• ✔️ Reduces viral load effectively.

• ✔️ Increases CD4+ T-cell count and strengthens immunity.

• ✔️ Delays progression of HIV to AIDS.

• ✔️ Ritonavir boosts lopinavir, reducing pill burden and improving results.

⚠️ Possible Side Effects

• Common: Nausea, diarrhea, stomach pain, headache, fatigue.

• Moderate: Increased cholesterol/triglycerides, liver enzyme elevation, changes in body fat distribution.

• Serious (rare): Pancreatitis, severe liver problems, abnormal heart rhythm.

🧾 Safety Advice

• 🚫 Avoid alcohol (increases liver side effects).

• ⚠️ Use with caution in patients with liver disease.

• 🧪 Regular monitoring of lipid profile, liver function, and viral load required.

• 🚫 Do not stop abruptly – may cause resistance.

• ✅ Take exactly as prescribed, even if you feel well.

❓ FAQs

1. What is Prolavir-LR used for?
➡️ It is used for the management of HIV-1 infection as part of ART.

2. Can Prolavir-LR cure HIV?
➡️ No, it does not cure HIV but helps control the infection and improve quality of life.

3. Why is ritonavir combined with lopinavir?
➡️ Ritonavir boosts lopinavir levels by slowing its breakdown, making the treatment more effective.

4. Can Prolavir-LR be taken during pregnancy?
➡️ Yes, it may be used in pregnancy under specialist guidance (commonly prescribed in prevention of mother-to-child transmission).

5. What should I do if I miss a dose?
➡️ Take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double dose.

🌍 Why Choose Medipills Pharma For Prolavir-LR?

• 💊 100% genuine & quality-assured HIV medicines.

• 🌐 Global delivery network with trusted logistics.

• 🏥 Supplying to hospitals, NGOs & clinics worldwide.

• 📦 Secure packing & fast shipping.

• ✅ Affordable pricing & professional support.